Prostate Cancer Treatment and Research

Latest papers

• Lesion-Aware Adaptive Fourier Neural Operator for CT-to-PSMA PET Synthesis in Prostate Cancer

  Rashmi Bhaskara, Waleed M. Almutairi, Matthew Gopaulchan, Maram Musaad Alqurashi, Francis Asamoah, Alex Ocana, Clinton D. Bahler, Oluwaseyi M. Oderinde · 12 August 2026

  Deep learning models that synthesize PET from CT or MRI can reduce patient dose and scanner demand, but are typically optimized with global losses such as L1 or mean squared error (MSE) that treat all voxels similarly. In whole-body PSMA-PET, tumor voxels occupy only a small fraction of the volume, …

• TheraAgent: Multi-Agent Framework with Self-Evolving Memory and Evidence-Calibrated Reasoning for PET Theranostics

  Zhihao Chen, Jiahui Wang, Yizhou Chen, Xiaozhong Ji, Xiaobin Hu, Jimin Hong, Wolfram Andreas Bosbach, Axel Rominger, Ali Afshar-Oromieh, Hongming Shan, Kuangyu Shi · 17 March 2026

  PET theranostics is transforming precision oncology, yet treatment response varies substantially; many patients receiving 177Lu-PSMA radioligand therapy (RLT) for metastatic castration-resistant prostate cancer (mCRPC) fail to respond, demanding reliable pre-therapy prediction. While LLM-based agent…

• Externally Validated Longitudinal GRU Model for Visit-Level 180-Day Mortality Risk in Metastatic Castration-Resistant Prostate Cancer

  Javier Mencia-Ledo, Mohammad Noaeen, Zahra Shakeri · 29 January 2026

  Metastatic castration-resistant prostate cancer (mCRPC) is a highly aggressive disease with poor prognosis and heterogeneous treatment response. In this work, we developed and externally validated a visit-level 180-day mortality risk model using longitudinal data from two Phase III cohorts (n=526 an…