Health Sciences › Medicine › Ophthalmology
Retinal Diseases and Treatments
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- Modelling Geographic Atrophy Progression using Implicit Neural Representations
Simone Sarrocco, Paul Friedrich, Florentin Bieder, Christina Bornberg, Philippe Valmaggia, Peter Maloca, Philippe Cattin · 12 August 2026
Age-related Macular Degeneration (AMD) is the major cause of blindness in the Western world. Its late dry phase is characterised by irreversible atrophic areas, namely Geographic Atrophy (GA). Longitudinal Fundus Autofluorescence (FAF) image acquisitions are currently the main tool for assessing les…
- OphthaDT: Generative Digital Twins for Forecasting Visual Acuity Trajectories in Ophthalmology
Pietro Belligoli, Nikita Makarov, Sayedali Shetab Boushehri, Fabian Schmich, Raul Rodriguez-Esteban, Michael Menden · 23 June 2026
Precision medicine in ophthalmology requires accurate longitudinal predictions, but the fragmented nature of multimodal clinical data remains a barrier to forecasting. We introduce OphthaDT, an LLM-based digital twin for ophthalmology that serializes longitudinal patient histories from 3,220 patient…
- Response-Aware Multimodal Learning for Post-Treatment Visual Acuity Forecasting
Phuoc-Nguyen Bui, Van-Vi Vo, Duc-Tai Le, Junghyun Bum, Van-Nguyen Pham, Ki-Young Kim, Seung-Young Yu, Hyunseung Choo · 2 June 2026
Long-term visual acuity (VA) outcomes after anti-VEGF therapy are central to patient counseling, expectation setting, and follow-up planning in diabetic macular edema (DME). However, in clinical practice, physicians must often estimate long-term visual trajectories based only on early post-treatment…
