Cutaneous Melanoma Detection and Management

Latest papers

• LENS-GRF: Permutation-Invariant Lesion Evidence Network with Gated Residual Fusion for Acne Severity Grading and Multi-Rater Clinical Oracle Analysis

  Muhammad Muhtasim Shahriar, M. F. Mridha · 2 October 2026

  Automated acne severity grading requires both whole-face context and fine-grained lesion evidence. We propose LENS-GRF (Lesion Evidence Network with Set-Transformer and Gated Residual Fusion), an interpretable multi-stage framework for four-class acne severity grading. The method combines Adaptive F…

• Detail in Context: A Dual-Scale Machine Learning Framework for Mycosis Fungoides Detection

  Mohamed Hazem, Tarek Waleed, Omar Khaled, Nada Omar, Mahmoud Raslan, Marwa Mohamed Fawzy, Aya Fahim, Rania M. Mogawer, Ahmed Mourad, Kariman Mansour, Muhammad Rushdi · 1 October 2026

  Mycosis fungoides (MF) is a rare form of cutaneous T-cell lymphoma that is often misdiagnosed in early stages due to its visual similarity to benign inflammatory dermatoses. Early and accurate diagnosis is critical for improving patient outcomes. In this paper, we propose a comprehensive diagnostic …

• How Medical VLMs Underutilize Their Vision Encoders: A Dermatology Perspective

  Janet Wang, Yunbei Zhang, Xiao Wang, Jihun Hamm · 30 September 2026

  Medical Vision-Language Models (VLMs) show significant promise for clinical image understanding, offering accurate diagnosis with interpretable reasoning. However, a critical performance gap exists between their strong vision encoders and the full multimodal model: in dermatology, the MedSigLIP enco…

• MDSkin-Net: Multi-Task Skin Lesion Analysis Driven by Pattern Analysis Priors and Spatial Alignment Regularization

  Yijian Li, Saad Bedros, Paul Bigliardi, Mei Bigliardi Qi, Vassilios Morellas, Nikolaos Papanikolopoulos · 28 September 2026

  Reliable skin lesion segmentation and classification are central to dermoscopic computer-aided diagnosis. Existing multi-task frameworks couple the two tasks architecturally without clinical knowledge, while knowledge-injecting approaches rely on the macroscopic ABCD rule, which was not designed for…

• CG-HAF: An Interpretable Global-Local Lesion-Burden Fusion Framework for Ordinal Acne Severity Grading in Agentic Skincare Support

  Muhammad Muhtasim Shahriar, Md. Naimur Asif Borno, Saad Aloteibi, Mohammad Ali Moni · 28 September 2026

  Ordinal acne severity grading requires distinguishing visually similar neighboring grades while jointly weighing holistic facial appearance and localized lesion burden - evidence that most existing approaches collapse into a single opaque representation. We introduce CG-HAF, a global-local fusion fr…

• MedTokenBudget: Lesion-Preserving Token Routing for Dermoscopic Image Classification

  Zhexiang Li · 28 September 2026

  Dermoscopy classifiers built on Vision Transformers process all image patches uniformly, although diagnostic evidence is concentrated in the lesion region. Existing token pruning methods reduce tokens using generic saliency or similarity signals, but rarely ask whether the retained subset still cont…

• Evidence-Driven Differential Diagnosis of Malignant Melanoma

  Naren Akash, Anirudh Kaushik, Jayanthi Sivaswamy · 25 September 2026

  We present a modular and multi-level framework for the differential diagnosis of malignant melanoma. Our framework integrates contextual information and evidence at the lesion, patient, and population levels, enabling decision-making at each level. We introduce an anatomic-site aware masked transfor…

• SkinAgent AI: A Safety-Grounded Multimodal Agentic Framework for Non-Diagnostic Skincare Support

  Muhammad Muhtasim Shahriar, Abdullah Mohammad Sayem, Tze Hui Liew, M. F. Mridha, Md. Mahiuddin · 25 September 2026

  Consumer-facing skincare AI must coordinate visual evidence, product information, tool use, and user-facing actions within explicit evidence and safety boundaries. This study evaluates SkinAgent AI, a non-diagnostic multimodal framework that combines visual concern routing with grounded and auditabl…

• Benchmarking Off-the-Shelf Multimodal AI Models Against Dermatologists on Patient-Captured Skin Images

  Rian Dolphin, Laura Knowles · 22 September 2026

  Artificial intelligence (AI) has advanced at a rapid pace in recent years. Initially, breakthroughs in large language models caught widespread attention. However, recent generations of frontier AI models have adopted multimodal capabilities as a first class citizen, with vision capabilities being ce…

• MoSSGate: Memory-Modulated State-Space Gating for Skin Lesion Segmentation

  Anum Awan, Mahnoor Buriro, Muhammad Younas Khan, Md Imam Ahasan · 18 September 2026

  Accurate skin lesion segmentation is crucial for reliable computer-aided dermatological diagnosis, yet existing convolutional and transformer-based models often struggle to jointly capture long-range spatial dependencies and fine boundary details under limited computational budgets. This trade-off b…

• Adaptive Conformal Redistribution for Inter-class Transitional Uncertainty in Medical Image Classification

  Saibal Ghosh, Samarup Bhattacharya, Sanjoy Kumar Saha, Umapada Pal, Tapabrata Chakraborti · 15 September 2026

  Medical image classification is frequently complicated by transitional categories whose feature distributions overlap those of adjacent classes, producing ambiguous decision boundaries. Conformal prediction returns uncertainty-aware prediction sets, but these are not directly actionable in clinical …

• A Comparative Evaluation of Pre-trained Convolutional Neural Networks for Melanoma Detection

  Wagner Moreno Schmitz, Marco Antonio de Castro Barbosa, Thiago Magalh\~aes Amaral, Dalcimar Casanova, Jefferson Tales Oliva · 11 September 2026

  Early diagnosis of melanoma is critical for improving patient survival rates. However, accurately distinguishing melanoma from other skin lesions remains a significant clinical challenge due to the high visual similarity among lesion types and variability in image acquisition conditions. Artificial …

• BruNet: A Cross-Domain Transfer Framework for Bruise Segmentation

  Qiming Wang, Richard J. Motley, Ebube E. Obi, Xianfang Sun, Paul L. Rosin · 11 September 2026

  Segmenting bruises is a challenging task in medical imaging due to limited data and annotations, diffuse boundaries, and highly variable appearance. In this work, we propose BruNet, a segmentation framework that combines a ViT-based visual encoder (a self-supervised DINOv3 or a pretrained LingBot-Vi…

• Deep Learning for Biopsy-Free Subtyping of Basal Cell Carcinoma from Dermatoscopic Images

  Alexandros Papadopoulos, Chrysa Episkopou, Ioannis Sarafis, Aimilios Lallas, Anastasios Delopoulos · 9 September 2026

  Basal Cell Carcinoma (BCC) is the most common type of skin cancer, accounting for nearly 80% of skin cancer di- agnoses. Its optimal clinical management is guided by the distinct histopathologic subtype, with aggressive variants requiring more drastic measures. In current clinical practice, subtypin…

• Beyond Blur: A Semantic Tri-view Pipeline for Teledermatology Gradability via Skin Micro-relief

  Robert Engel · 4 September 2026

  Smartphone skin photographs are indispensable to teledermatology, yet assessing the diagnostic suitability of submitted cases (gradability) remains a critical bottleneck in mobile care workflows. Dermatologists routinely review multiple photographic views (regional, angled, and close-up) to identify…

• Disease Burden over Skin Tone: Decomposing the Dermatology-AI Generalization Gap

  Nirajan Kunwor, Sanjaya Poudel, Quoc-Huy Trinh, Jahidul Arafat, Sunil Kumar Gaire · 3 September 2026

  Dermatology artificial intelligence (AI) models are predominantly trained on light-skinned, cancer-focused image collections, yet they are increasingly proposed for deployment in resource-constrained settings where patients differ from training populations along two confounded axes: skin tone and di…

• Deep Feature Pyramid Convolutional Networks with In-Place Activated Batch Normalization for Automated Skin Lesion Boundary Segmentation

  Glib Kechyn · 26 August 2026

  Segmentation of skin lesion boundaries in dermoscopic imaging is an important prerequisite step for computer-aided diagnosis of malignant melanoma, but remains challenging due to fuzzy margins, occluding artifacts such as hair and blood vessels, low contrast, and high inter-patient variability. This…

• MIFR: A Modality-Invariant and Fair Representation Framework for Skin Disease Classification

  Asonyu Senge Njih, Yvan Guifo Fodjo, Vianney Kengne Tchendji, Jerry Lacmou Zeutouo, Kerol Djoumessi · 20 August 2026

  Skin diseases represent a major global public health burden, yet machine learning tools developed to assist in their diagnosis suffer from two critical limitations: reliance on only one modality for diagnosis and systematic performance disparities across skin tones. While existing approaches address…

• Picking the Right Image to Classify: Reliable-Input Selection in Teledermatology

  Fabian Gröger, Marco Weishaupt, Philippe Gottfrois, Simone Lionetti, Linda Wermelinger, Nipun Ranasekara, Ludovic Amruthalingam, Alexander A. Navarini, Marc Pouly · 18 August 2026

  Dermatology models face distribution shifts in teledermatology settings, where submitted images differ from the training data in lighting, angle, distance, focus, and framing. These test-time images are ordinary clinical photographs, but some fall outside the model's training conditions, leading the…

• EA-LiteUNet: An Edge-Adaptive and Resource-Efficient U-Net for Boundary-Sensitive Dermoscopic Image Segmentation

  Wang Jiangtao, Nur Intan Raihana Ruhaiyem, Fu Panpan, Yang Yu, Huang Yan · 18 August 2026

  Accurate boundary delineation remains a persistent challenge in dermoscopic image segmentation because of blurred lesion margins, heterogeneous textures, and complex background artifacts. From a signal-processing perspective, lesion boundaries represent high-frequency components that are highly susc…

• Uncertainty Identifies Difficult Samples Across Methods: A Multi-Task Study on a Heterogeneous Skin Lesion Dataset

  Leon Koole, Jiapan Guo, Matias Valdenegro-Toro · 17 August 2026

  Skin lesion classifiers can be confidently wrong on the cases that matter most, so knowing when a prediction should not be trusted is clinically as useful as the prediction. We study uncertainty quantification on a dataset pooled from many ISIC sources, with a shared backbone and two jointly learned…

• Soft-Attention Improves Skin Cancer Classification Performance

  Soumyya Kanti Datta, Seyed Mohammad Abuzar Hashemi, Sargur N. Srihari, Mingchen Gao · 13 August 2026

  In clinical applications, neural networks must focus on and highlight the most important parts of an input image. Soft-Attention mechanism enables a neural network toachieve this goal. This paper investigates the effectiveness of Soft-Attention in deep neural architectures. The central aim of Soft-A…

• Uncertainty-Aware and Explainable Ensemble Deep Learning Framework for Multi-Class Skin Lesion Classification

  Rofiqul Islam, Lilatul Ferdouse · 13 August 2026

  Skin cancer diagnosis from dermoscopic images remains challenging due to high intra-class variability, inter-class similarity, class imbalance, and the limited interpretability of deep learning models. This paper proposes an uncertainty-aware and explainable deep learning framework for multi-class s…

• Multimodal Skin Lesion Classification with Swin Transformer and Clinical Metadata Fusion

  Nethmi Pathirana, Isuru Munasinghe, Dileeka Alwis · 5 August 2026

  Skin lesion classification plays an important role in supporting the early diagnosis of skin cancer. However, automated analysis remains challenging due to class imbalance, inter-class similarity, and intra-class variability in dermoscopic images. This paper proposes a multimodal classification fram…

• Open-Linguistic Concept Unified Learning for Cross-Site Interpretable Dermatology Image Diagnosis

  Chengyu Wu, Junpeng Tan, Wanxiang Luo, Yaqi Wang, Yandong Wen, Yefeng Zheng · 5 August 2026

  Human-interpretable computer-aided diagnosis is crucial for clinical decision making. Concept-based models excel by providing transparent reasoning and enabling post-hoc, clinician-in-the-loop interventions. However, their rigid dataset-specific adaptation inherently restricts cross-site generalizat…